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BMCBI
2007
126views more  BMCBI 2007»
15 years 6 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
COMPLEXITY
2006
91views more  COMPLEXITY 2006»
15 years 6 months ago
The evolution of technology within a simple computer model
Technology--the collection of devices and methods available to human society--evolves by constructing new devices and methods from ones that previously exist, and in turn offering...
W. Brian Arthur, Wolfgang Polak
GECCO
2004
Springer
127views Optimization» more  GECCO 2004»
15 years 11 months ago
Computational Complexity and Simulation of Rare Events of Ising Spin Glasses
We discuss the computational complexity of random 2D Ising spin glasses, which represent an interesting class of constraint satisfaction problems for black box optimization. Two ex...
Martin Pelikan, Jiri Ocenasek, Simon Trebst, Matth...
BMCBI
2011
15 years 1 months ago
A discriminative method for family-based protein remote homology detection that combines inductive logic programming and proposi
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
Juliana S. Bernardes, Alessandra Carbone, Gerson Z...
BIRD
2008
Springer
131views Bioinformatics» more  BIRD 2008»
15 years 8 months ago
Identifying Subcellular Locations from Images of Unknown Resolution
Our group has previously used machine learning techniques to develop computational systems to automatically analyse fluorescence microscope images and classify the location of the ...
Luís Pedro Coelho, Robert F. Murphy