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BMCBI
2007
115views more  BMCBI 2007»
15 years 6 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
JANCL
2008
109views more  JANCL 2008»
15 years 6 months ago
Conditionalization and total knowledge
This paper employs epistemic logic to investigate the philosophical foundations of Bayesian updating in belief revision. By Bayesian updating, we understand the tenet that an agen...
Ian Pratt-Hartmann
JCB
2006
124views more  JCB 2006»
15 years 6 months ago
The Average Common Substring Approach to Phylogenomic Reconstruction
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
Igor Ulitsky, David Burstein, Tamir Tuller, Benny ...
BMCBI
2005
133views more  BMCBI 2005»
15 years 6 months ago
Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Hélène Chiapello, I. Bourgait, F. So...
BMCBI
2005
141views more  BMCBI 2005»
15 years 6 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...