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BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
Predicting population coverage of T-cell epitope-based diagnostics and vaccines
Background: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a...
Huynh-Hoa Bui, John Sidney, Kenny Dinh, Scott Sout...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces
Background: Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that go...
Joan Teyra, Andreas Doms, Michael Schroeder, M. Te...
BMCBI
2006
172views more  BMCBI 2006»
15 years 6 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
BMCBI
2006
140views more  BMCBI 2006»
15 years 6 months ago
SNP-PHAGE - High throughput SNP discovery pipeline
Background: Single nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...