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BMCBI
2010
103views more  BMCBI 2010»
15 years 7 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
BMCBI
2008
121views more  BMCBI 2008»
15 years 7 months ago
GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical proce...
Andreas Keller, Christina Backes, Maher Al-Awadhi,...
BMCBI
2006
150views more  BMCBI 2006»
15 years 6 months ago
TreeDyn: towards dynamic graphics and annotations for analyses of trees
Background: Analyses of biomolecules for biodiversity, phylogeny or structure/function studies often use graphical tree representations. Many powerful tree editors are now availab...
François Chevenet, Christine Brun, Anne-Lau...
BMCBI
2007
120views more  BMCBI 2007»
15 years 6 months ago
Non-coding sequence retrieval system for comparative genomic analysis of gene regulatory elements
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
Sung Tae Doh, Yunyu Zhang, Matthew H. Temple, Li C...
BMCBI
2005
187views more  BMCBI 2005»
15 years 6 months ago
JAtlasView: a Java atlas-viewer for browsing biomedical 3D images and atlases
Background: Many three-dimensional (3D) images are routinely collected in biomedical research and a number of digital atlases with associated anatomical and other information have...
Guangjie Feng, Nick Burton, Bill Hill, Duncan Davi...