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BMCBI
2005
122views more  BMCBI 2005»
15 years 6 months ago
Computational verification of protein-protein interactions by orthologous co-expression
Background: High-throughput methods identify an overwhelming number of protein-protein interactions. However, the limited accuracy of these methods results in the false identifica...
Itay Tirosh, Naama Barkai
BMCBI
2005
159views more  BMCBI 2005»
15 years 6 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...
BMCBI
2005
108views more  BMCBI 2005»
15 years 6 months ago
Storing, linking, and mining microarray databases using SRS
Background: SRS (Sequence Retrieval System) has proven to be a valuable platform for storing, linking, and querying biological databases. Due to the availability of a broad range ...
Antoine Veldhoven, Don de Lange, Marcel Smid, Vict...
BMCBI
2005
135views more  BMCBI 2005»
15 years 6 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
BMCBI
2005
167views more  BMCBI 2005»
15 years 6 months ago
Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes
Background: The extensive use of DNA microarray technology in the characterization of the cell transcriptome is leading to an ever increasing amount of microarray data from cancer...
Patrick Warnat, Roland Eils, Benedikt Brors
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