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161
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BMCBI
2007
15 years 6 months ago
2007
Background: Sequencing of prokaryotic genomes has recently revealed the presence of CRISPR elements: short, highly conserved repeats separated by unique sequences of similar lengt...
154
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BMCBI
2007
15 years 6 months ago
2007
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
187
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BMCBI
2007
15 years 6 months ago
2007
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
205
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BMCBI
2007
15 years 6 months ago
2007
Background: Arabidopsis thaliana is the model species of current plant genomic research with a genome size of 125 Mb and approximately 28,000 genes. The function of half of these ...
183
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BMCBI
2007
15 years 6 months ago
2007
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...