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BMCBI
2006
15 years 6 months ago
2006
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
180
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BMCBI
2006
15 years 6 months ago
2006
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...
179
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BMCBI
2006
15 years 6 months ago
2006
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
135
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BMCBI
2006
15 years 6 months ago
2006
Background: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a...
171
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BMCBI
2006
15 years 6 months ago
2006
Background: The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low th...