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BMCBI
2008
95views more  BMCBI 2008»
15 years 6 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
179
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BMCBI
2007
153views more  BMCBI 2007»
15 years 6 months ago
MPHASYS: a mouse phenotype analysis system
Background: Systematic, high-throughput studies of mouse phenotypes have been hampered by the inability to analyze individual animal data from a multitude of sources in an integra...
R. Brent Calder, Rudolf B. Beems, Harry van Steeg,...
177
Voted
BMCBI
2007
168views more  BMCBI 2007»
15 years 6 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
BMCBI
2008
94views more  BMCBI 2008»
15 years 6 months ago
Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
Background: Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for developing vac...
Ruchi Verma, Ajit Tiwari, Sukhwinder Kaur, Grish C...
BMCBI
2008
110views more  BMCBI 2008»
15 years 6 months ago
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated da
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
Neil F. W. Saunders, Ross I. Brinkworth, Thomas Hu...
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