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BMCBI
2008
110views more  BMCBI 2008»
15 years 6 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
BMCBI
2008
182views more  BMCBI 2008»
15 years 6 months ago
MiMiR - an integrated platform for microarray data sharing, mining and analysis
Background: Despite considerable efforts within the microarray community for standardising data format, content and description, microarray technologies present major challenges i...
Chris Tomlinson, Manjula Thimma, Stelios Alexandra...
BMCBI
2008
131views more  BMCBI 2008»
15 years 6 months ago
Major copy proportion analysis of tumor samples using SNP arrays
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
Cheng Li, Rameen Beroukhim, Barbara A. Weir, Wendy...
BMCBI
2008
104views more  BMCBI 2008»
15 years 6 months ago
Missing value imputation improves clustering and interpretation of gene expression microarray data
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
Johannes Tuikkala, Laura Elo, Olli Nevalainen, Ter...
BMCBI
2008
118views more  BMCBI 2008»
15 years 6 months ago
MetWAMer: eukaryotic translation initiation site prediction
Background: Translation initiation site (TIS) identification is an important aspect of the gene annotation process, requisite for the accurate delineation of protein sequences fro...
Michael E. Sparks, Volker Brendel
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