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BMCBI
2007
181views more  BMCBI 2007»
15 years 7 months ago
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Seth I. Berger, Jeremy M. Posner, Avi Ma'ayan
BMCBI
2008
121views more  BMCBI 2008»
15 years 7 months ago
Modularization of biochemical networks based on classification of Petri net t-invariants
Background: Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from ...
Eva Grafahrend-Belau, Falk Schreiber, Monika Heine...
BMCBI
2008
145views more  BMCBI 2008»
15 years 7 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
163views more  BMCBI 2008»
15 years 7 months ago
Nuclear staining and relative distance for quantifying epidermal differentiation in biomarker expression profiling
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
Thora Pommerencke, Thorsten Steinberg, Hartmut Dic...
ICSE
2008
IEEE-ACM
16 years 7 months ago
Predicting defects using network analysis on dependency graphs
In software development, resources for quality assurance are limited by time and by cost. In order to allocate resources effectively, managers need to rely on their experience bac...
Thomas Zimmermann, Nachiappan Nagappan