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203
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BMCBI
2011
15 years 1 months ago
2011
Background: High-throughput screening (HTS) is a key part of the drug discovery process during which thousands of chemical compounds are screened and their activity levels measure...
216
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BMCBI
2011
15 years 1 months ago
2011
Background: Typical analysis of microarray data ignores the correlation between gene expression values. In this paper we present a model for microarray data which specifically all...
215
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BMCBI
2011
15 years 1 months ago
2011
Background: In rule-based modeling, graphs are used to represent molecules: a colored vertex represents a component of a molecule, a vertex attribute represents the internal state...
220
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BMCBI
2011
15 years 1 months ago
2011
Background: Large databases of genetic data are often biased in their representation. Thus, selection of genetic data with desired properties, such as evolutionary representation ...
234
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BMCBI
2011
15 years 1 months ago
2011
Background: DNA microarrays have become a nearly ubiquitous tool for the study of human disease, and nowhere is this more true than in cancer. With hundreds of studies and thousan...