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BMCBI
2011
15 years 1 months ago
iPhy: an integrated phylogenetic workbench for supermatrix analyses
Background: The increasing availability of molecular sequence data means that the accuracy of future phylogenetic studies is likely to by limited by systematic bias and taxon choi...
Martin O. Jones, Georgios D. Koutsovoulos, Mark L....
BMCBI
2011
15 years 1 months ago
VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R
Background: Visualization of orthogonal (disjoint) or overlapping datasets is a common task in bioinformatics. Few tools exist to automate the generation of extensively-customizab...
Hanbo Chen, Paul C. Boutros
BMCBI
2011
15 years 1 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
BMCBI
2011
15 years 1 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
BMCBI
2011
15 years 1 months ago
CODA (CrossOver Distribution Analyzer): quantitative characterization of crossover position patterns along chromosomes
Background: During meiosis, homologous chromosomes exchange segments via the formation of crossovers. This phenomenon is highly regulated; in particular, crossovers are distribute...
Franck Gauthier, Olivier C. Martin, Matthieu Falqu...
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