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IJCNN
2008
IEEE
16 years 1 months ago
On the sample mean of graphs
— We present an analytic and geometric view of the sample mean of graphs. The theoretical framework yields efficient subgradient methods for approximating a structural mean and ...
Brijnesh J. Jain, Klaus Obermayer
BMCBI
2006
125views more  BMCBI 2006»
15 years 6 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
BMCBI
2007
128views more  BMCBI 2007»
15 years 6 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
ALMOB
2008
82views more  ALMOB 2008»
15 years 6 months ago
Protein sequence and structure alignments within one framework
Background: Protein structure alignments are usually based on very different techniques to sequence alignments. We propose a method which treats sequence, structure and even combi...
Gundolf Schenk, Thomas Margraf, Andrew E. Torda
BMCBI
2010
106views more  BMCBI 2010»
15 years 6 months ago
Multiple structure alignment and consensus identification for proteins
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructu...
Ivaylo Ilinkin, Jieping Ye, Ravi Janardan