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» Approximate Structural Consistency
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BMCBI
2007
97views more  BMCBI 2007»
15 years 6 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2007
216views more  BMCBI 2007»
15 years 6 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
183
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BMCBI
2007
144views more  BMCBI 2007»
15 years 6 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
ALIFE
2005
15 years 6 months ago
Material Representations: From the Genetic Code to the Evolution of Cellular Automata
We present a new definition of the concept of representation for cognitive science that is based on a study of the origin of structures that are used to store memory in evolving sy...
Luis Mateus Rocha, Wim Hordijk
BMCBI
2005
92views more  BMCBI 2005»
15 years 6 months ago
FIGENIX: Intelligent automation of genomic annotation: expertise integration in a new software platform
Background: Two of the main objectives of the genomic and post-genomic era are to structurally and functionally annotate genomes which consists of detecting genes' position a...
Philippe Gouret, Vérane Vitiello, Nathalie ...