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JIB
2006
220views more  JIB 2006»
15 years 6 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
BMCBI
2005
133views more  BMCBI 2005»
15 years 6 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
BIBM
2010
IEEE
157views Bioinformatics» more  BIBM 2010»
15 years 4 months ago
Decomposing PPI networks for complex discovery
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...
BMCBI
2010
122views more  BMCBI 2010»
15 years 1 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
PROMISE
2010
15 years 1 months ago
Case-based reasoning vs parametric models for software quality optimization
Background: There are many data mining methods but few comparisons between them. For example, there are at least two ways to build quality optimizers, programs that find project o...
Adam Brady, Tim Menzies