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BMCBI
2010
113views more  BMCBI 2010»
15 years 6 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
BMCBI
2007
176views more  BMCBI 2007»
15 years 6 months ago
The Firegoose: two-way integration of diverse data from different bioinformatics web resources with desktop applications
Background: Information resources on the World Wide Web play an indispensable role in modern biology. But integrating data from multiple sources is often encumbered by the need to...
J. Christopher Bare, Paul T. Shannon, Amy K. Schmi...
BMCBI
2006
88views more  BMCBI 2006»
15 years 6 months ago
RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Jean-François Lucier, Lucien Junior Bergero...
PR
2006
164views more  PR 2006»
15 years 6 months ago
Locally linear metric adaptation with application to semi-supervised clustering and image retrieval
Many computer vision and pattern recognition algorithms are very sensitive to the choice of an appropriate distance metric. Some recent research sought to address a variant of the...
Hong Chang, Dit-Yan Yeung
BMCBI
2005
119views more  BMCBI 2005»
15 years 6 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona