Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Background: Many biological functions involve various protein-protein interactions (PPIs). Elucidating such interactions is crucial for understanding general principles of cellula...
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
Background: There is a need for software applications that provide users with a complete and extensible toolkit for chemo- and bioinformatics accessible from a single workbench. C...
Ola Spjuth, Tobias Helmus, Egon L. Willighagen, St...
Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification...