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JIB
2006
106views more  JIB 2006»
15 years 6 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
NAR
2008
165views more  NAR 2008»
15 years 6 months ago
4DXpress: a database for cross-species expression pattern comparisons
In the major animal model species like mouse, fish or fly, detailed spatial information on gene expression over time can be acquired through whole mount in situ hybridization expe...
Yannick Haudry, Hugo Berube, Ivica Letunic, Paul-D...
NAR
2008
107views more  NAR 2008»
15 years 6 months ago
ISPIDER Central: an integrated database web-server for proteomics
Despite the growing volumes of proteomic data, integration of the underlying results remains problematic owing to differences in formats, data captured, protein accessions and ser...
Jennifer A. Siepen, Khalid Belhajjame, Julian N. S...
SIGIR
2008
ACM
15 years 6 months ago
Learning from labeled features using generalized expectation criteria
It is difficult to apply machine learning to new domains because often we lack labeled problem instances. In this paper, we provide a solution to this problem that leverages domai...
Gregory Druck, Gideon S. Mann, Andrew McCallum
BMCBI
2005
125views more  BMCBI 2005»
15 years 6 months ago
Query3d: a new method for high-throughput analysis of functional residues in protein structures
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
Gabriele Ausiello, Allegra Via, Manuela Helmer-Cit...