K42 is one of the few recent research projects that is examining operating system design structure issues in the context of new whole-system design. K42 is open source and was des...
Orran Krieger, Marc A. Auslander, Bryan S. Rosenbu...
Background: MicroRNAs (miRNAs) are endogenous small RNAs that play a key role in post-transcriptional regulation of gene expression in animals and plants. The number of known miRN...
Anders Jacobsen, Anders Krogh, Sakari Kauppinen, M...
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
Background: Broad-based collaborations are becoming increasingly common among disease researchers. For example, the Global HIV Enterprise has united cross-disciplinary consortia t...
Elizabeth K. Nelson, Britt Piehler, Josh Eckels, A...
I have been designing and building applications, including the databases used by those applications, for several decades now. I have seen similar problems approached by different d...