Background: Life processes are determined by the organism's genetic profile and multiple environmental variables. However the interaction between these factors is inherently ...
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...
Background: Normalization in real-time qRT-PCR is necessary to compensate for experimental variation. A popular normalization strategy employs reference gene(s), which may introdu...
It is important in bioinformatics research and applications to select or discover informative genes of a tumor from microarray data. However, most of the existing methods are based...
We develop a method for integrating time series expression profiles and factor-gene binding data to quantify dynamic aspects of gene regulation. We estimate latencies for transcr...