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» Analysis of Agglomerative Clustering
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BMCBI
2008
100views more  BMCBI 2008»
15 years 6 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
DEBU
2008
186views more  DEBU 2008»
15 years 6 months ago
A Survey of Collaborative Recommendation and the Robustness of Model-Based Algorithms
The open nature of collaborative recommender systems allows attackers who inject biased profile data to have a significant impact on the recommendations produced. Standard memory-...
Jeff J. Sandvig, Bamshad Mobasher, Robin D. Burke
DKE
2008
79views more  DKE 2008»
15 years 6 months ago
Extracting k most important groups from data efficiently
We study an important data analysis operator, which extracts the k most important groups from data (i.e., the k groups with the highest aggregate values). In a data warehousing co...
Man Lung Yiu, Nikos Mamoulis, Vagelis Hristidis
BMCBI
2006
170views more  BMCBI 2006»
15 years 6 months ago
Biclustering of gene expression data by non-smooth non-negative matrix factorization
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...
BMCBI
2006
143views more  BMCBI 2006»
15 years 6 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...