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» Analysis of Agglomerative Clustering
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BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-or
Background: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to ...
Eelke van der Horst, Julio E. Peironcely, Adriaan ...
BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
BMCBI
2008
145views more  BMCBI 2008»
15 years 6 months ago
Directed acyclic graph kernels for structural RNA analysis
Background: Recent discoveries of a large variety of important roles for non-coding RNAs (ncRNAs) have been reported by numerous researchers. In order to analyze ncRNAs by kernel ...
Kengo Sato, Toutai Mituyama, Kiyoshi Asai, Yasubum...
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour
BMCBI
2007
198views more  BMCBI 2007»
15 years 6 months ago
Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation
Time course gene expression experiments are a popular means to infer co-expression. Many methods have been proposed to cluster genes or to build networks based on similarity measu...
Nicola Neretti, Daniel Remondini, Marc Tatar, John...