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BMCBI
2010
147views more  BMCBI 2010»
15 years 7 months ago
CNstream: A method for the identification and genotyping of copy number polymorphisms using Illumina microarrays
Background: Understanding the genetic basis of disease risk in depth requires an exhaustive knowledge of the types of genetic variation. Very recently, Copy Number Variants (CNVs)...
Arnald Alonso, Antonio Julià, Raül Tor...
BMCBI
2010
108views more  BMCBI 2010»
15 years 7 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2008
148views more  BMCBI 2008»
15 years 7 months ago
StAR: a simple tool for the statistical comparison of ROC curves
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
Ismael A. Vergara, Tomás Norambuena, Evandr...
BMCBI
2010
133views more  BMCBI 2010»
15 years 7 months ago
Integrated prediction of one-dimensional structural features and their relationships with conformational flexibility in helical
Background: Many structural properties such as solvent accessibility, dihedral angles and helix-helix contacts can be assigned to each residue in a membrane protein. Independent s...
Shandar Ahmad, Yumlembam Hemjit Singh, Yogesh Paud...
BMCBI
2007
105views more  BMCBI 2007»
15 years 7 months ago
Generating confidence intervals on biological networks
Background: In the analysis of networks we frequently require the statistical significance of some network statistic, such as measures of similarity for the properties of interact...
Thomas Thorne, Michael P. H. Stumpf