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CASCON
1997
91views Education» more  CASCON 1997»
15 years 8 months ago
Keeping virtual information resources up and running
The maintenanceofmaterializedviews in largescale environments composed of numerous heterogeneous information sources ISs, such as the WWW, has importance for the new breed of in...
Amy J. Lee, Anisoara Nica, Elke A. Rundensteiner
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2007
135views more  BMCBI 2007»
15 years 6 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer
DAC
2006
ACM
16 years 7 months ago
Statistical timing based on incomplete probabilistic descriptions of parameter uncertainty
Existing approaches to timing analysis under uncertainty are based on restrictive assumptions. Statistical STA techniques assume that the full probabilistic distribution of parame...
Wei-Shen Wang, Vladik Kreinovich, Michael Orshansk...
KDD
2009
ACM
178views Data Mining» more  KDD 2009»
16 years 7 months ago
Constrained optimization for validation-guided conditional random field learning
Conditional random fields(CRFs) are a class of undirected graphical models which have been widely used for classifying and labeling sequence data. The training of CRFs is typicall...
Minmin Chen, Yixin Chen, Michael R. Brent, Aaron E...
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