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BMCBI
2010
205views more  BMCBI 2010»
15 years 7 months ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
BMCBI
2006
144views more  BMCBI 2006»
15 years 6 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
244
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BMCBI
2005
156views more  BMCBI 2005»
15 years 6 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer
DKE
1998
88views more  DKE 1998»
15 years 6 months ago
Temporal Grid File: A File Structure for Interval Data
Disk I/O is a major bottleneck for query processing in database applications. This bottleneck is especially a problem for temporal databases because of their large size. Reduction...
Chiang Lee, Te-Ming Tseng
ICDE
2009
IEEE
140views Database» more  ICDE 2009»
16 years 8 months ago
Predicting Multiple Metrics for Queries: Better Decisions Enabled by Machine Learning
One of the most challenging aspects of managing a very large data warehouse is identifying how queries will behave before they start executing. Yet knowing their performance charac...
Archana Ganapathi, Harumi A. Kuno, Umeshwar Dayal,...