Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Disk I/O is a major bottleneck for query processing in database applications. This bottleneck is especially a problem for temporal databases because of their large size. Reduction...
One of the most challenging aspects of managing a very large data warehouse is identifying how queries will behave before they start executing. Yet knowing their performance charac...
Archana Ganapathi, Harumi A. Kuno, Umeshwar Dayal,...