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204
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BMCBI
2010
15 years 7 months ago
2010
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
200
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BMCBI
2010
15 years 7 months ago
2010
Background: Systems biologists are faced with the difficultly of analyzing results from large-scale studies that profile the activity of many genes, RNAs and proteins, applied in ...
194
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BMCBI
2010
15 years 7 months ago
2010
Background: Multiplex Ligation-Dependent Probe Amplification (MLPA) is an application that can be used for the detection of multiple chromosomal aberrations in a single experiment...
198
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BMCBI
2010
15 years 7 months ago
2010
Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
203
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BMCBI
2010
15 years 7 months ago
2010
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...