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BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
permGPU: Using graphics processing units in RNA microarray association studies
Background: Many analyses of microarray association studies involve permutation, bootstrap resampling and crossvalidation, that are ideally formulated as embarrassingly parallel c...
Ivo D. Shterev, Sin-Ho Jung, Stephen L. George, Ko...
BMCBI
2010
133views more  BMCBI 2010»
15 years 6 months ago
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
Anup Parikh, Eryong Huang, Christopher Dinh, Blaz ...
BMCBI
2010
113views more  BMCBI 2010»
15 years 6 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
BMCBI
2010
115views more  BMCBI 2010»
15 years 6 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2008
87views more  BMCBI 2008»
15 years 6 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
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