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170
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BMCBI
2010
15 years 6 months ago
2010
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
196
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BMCBI
2010
15 years 6 months ago
2010
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
160
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BMCBI
2010
15 years 6 months ago
2010
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
168
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BMCBI
2010
2010
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
15 years 6 months ago
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
163
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BMCBI
2010
15 years 6 months ago
2010
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...