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144
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BMCBI
2008
15 years 6 months ago
2008
Background: We consider effects of dependence among variables of high-dimensional data in multiple hypothesis testing problems, in particular the False Discovery Rate (FDR) contro...
199
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BMCBI
2008
15 years 6 months ago
2008
Background: Temporal gene expression profiles characterize the time-dynamics of expression of specific genes and are increasingly collected in current gene expression experiments....
163
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BMCBI
2008
15 years 6 months ago
2008
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
162
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BMCBI
2008
15 years 6 months ago
2008
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
184
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BMCBI
2008
15 years 6 months ago
2008
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...