A central challenge in systems biology is the reconstruction of biological networks from high-throughput data sets. A particularly difficult case of this is the inference of dynami...
Michael Baym, Chris Bakal, Norbert Perrimon, Bonni...
For as long as biologists have been computing alignments of sequences, the question of what values to use for scoring substitutions and gaps has persisted. While some choices for s...
Whether common ancestors of eukaryotes and prokaryotes had introns is one of the oldest unanswered questions in molecular evolution. Recently completed genome sequences have been u...
Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing protein interaction networks for various species at a...
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...