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JBI
2006
15 years 6 months ago
From concepts to clinical reality: An essay on the benchmarking of biomedical terminologies
It is only by fixing on agreed meanings of terms in biomedical terminologies that we will be in a position to achieve that accumulation and integration of knowledge that is indisp...
Barry Smith
NAR
2006
120views more  NAR 2006»
15 years 6 months ago
TreeDomViewer: a tool for the visualization of phylogeny and protein domain structure
Phylogenetic analysis and examination of protein domains allow accurate genome annotation and are invaluable to study proteins and protein complex evolution. However, two sequence...
Blaise T. F. Alako, Daphne Rainey, Harm Nijveen, J...
BMCBI
2005
137views more  BMCBI 2005»
15 years 6 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
BMCBI
2005
133views more  BMCBI 2005»
15 years 6 months ago
Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Hélène Chiapello, I. Bourgait, F. So...
BMCBI
2005
100views more  BMCBI 2005»
15 years 6 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...