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BMCBI
2005
82views more  BMCBI 2005»
15 years 6 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
TJS
2008
105views more  TJS 2008»
15 years 6 months ago
Using a relational database for scalable XML search
XML is a flexible and powerful tool that enables information and security sharing in heterogeneous environments. Scalable technologies are needed to effectively manage the growing...
Rebecca Cathey, Steven M. Beitzel, Eric C. Jensen,...
BMCBI
2005
93views more  BMCBI 2005»
15 years 6 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
BMCBI
2005
141views more  BMCBI 2005»
15 years 6 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
TKDE
2008
127views more  TKDE 2008»
15 years 6 months ago
Maximal Subspace Coregulated Gene Clustering
Clustering is a popular technique for analyzing microarray data sets, with n genes and m experimental conditions. As explored by biologists, there is a real need to identify coregu...
Yuhai Zhao, Jeffrey Xu Yu, Guoren Wang, Lei Chen 0...
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