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BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...
BMCBI
2006
129views more  BMCBI 2006»
15 years 6 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2006
135views more  BMCBI 2006»
15 years 6 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
BMCBI
2006
113views more  BMCBI 2006»
15 years 6 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2006
223views more  BMCBI 2006»
15 years 6 months ago
PSMIX: an R package for population structure inference via maximum likelihood method
Background: Inference of population stratification and individual admixture from genetic markers is an integrative part of a study in diverse situations, such as association mappi...
Baolin Wu, Nianjun Liu, Hongyu Zhao
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