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BMCBI
2006
103views more  BMCBI 2006»
15 years 6 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2006
108views more  BMCBI 2006»
15 years 6 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner
BMCBI
2006
151views more  BMCBI 2006»
15 years 6 months ago
Modeling Sage data with a truncated gamma-Poisson model
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
SNA - a toolbox for the stoichiometric analysis of metabolic networks
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
Robert Urbanczik
BMCBI
2006
156views more  BMCBI 2006»
15 years 6 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
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