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BMCBI
2008
167views more  BMCBI 2008»
15 years 6 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2008
150views more  BMCBI 2008»
15 years 6 months ago
MOSAIC: an online database dedicated to the comparative genomics of bacterial strains at the intra-species level
Background: The recent availability of complete sequences for numerous closely related bacterial genomes opens up new challenges in comparative genomics. Several methods have been...
Hélène Chiapello, Annie Gendrault, C...
BMCBI
2008
127views more  BMCBI 2008»
15 years 6 months ago
Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides
Background: Promoter region plays an important role in determining where the transcription of a particular gene should be initiated. Computational prediction of eukaryotic Pol II ...
Jian-Yi Yang, Yu Zhou, Zu-Guo Yu, Vo Anh, Li-Qian ...
BMCBI
2008
107views more  BMCBI 2008»
15 years 6 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....
BMCBI
2008
171views more  BMCBI 2008»
15 years 6 months ago
A general approach to simultaneous model fitting and variable elimination in response models for biological data with many more
Background: With the advent of high throughput biotechnology data acquisition platforms such as micro arrays, SNP chips and mass spectrometers, data sets with many more variables ...
Harri T. Kiiveri
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