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BMCBI
2010
148views more  BMCBI 2010»
15 years 6 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2010
98views more  BMCBI 2010»
15 years 6 months ago
Prediction of protein structural classes for low-homology sequences based on predicted secondary structure
Background: Prediction of protein structural classes (a, b, a + b and a/b) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulat...
Jian-Yi Yang, Zhen-Ling Peng, Xin Chen
BMCBI
2010
147views more  BMCBI 2010»
15 years 6 months ago
baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data
Background: High throughput sequencing has become an important technology for studying expression levels in many types of genomic, and particularly transcriptomic, data. One key w...
Thomas J. Hardcastle, Krystyna A. Kelly
CORR
2010
Springer
95views Education» more  CORR 2010»
15 years 6 months ago
Performance evaluation for ML sequence detection in ISI channels with Gauss Markov Noise
Inter-symbol interference (ISI) channels with data dependent Gauss Markov noise have been used to model read channels in magnetic recording and other data storage systems. The Vite...
Naveen Kumar, Aditya Ramamoorthy, Murti V. Salapak...
BMCBI
2007
106views more  BMCBI 2007»
15 years 6 months ago
Simultaneous identification of long similar substrings in large sets of sequences
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
Jürgen Kleffe, Friedrich Möller, Burghar...