Clinical databases store large amounts of information about patients and their medical conditions. Data mining techniques can extract relationships and patterns holding in this we...
Michele Berlingerio, Francesco Bonchi, Fosca Giann...
Residue coevolution has recently emerged as an important concept, especially in the context of protein structures. While a multitude of different functions for quantifying it have...
Kevin Y. Yip, Prianka Patel, Philip M. Kim, Donald...
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...