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BMCBI
2007
157views more  BMCBI 2007»
15 years 6 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
BMCBI
2007
116views more  BMCBI 2007»
15 years 6 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
BMCBI
2005
75views more  BMCBI 2005»
15 years 6 months ago
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
Hartmut Scheel, Kay Hofmann
SIAMIS
2011
15 years 1 months ago
A New Geometric Metric in the Space of Curves, and Applications to Tracking Deforming Objects by Prediction and Filtering
We define a novel metric on the space of closed planar curves which decomposes into three intuitive components. According to this metric centroid translations, scale changes and ...
Ganesh Sundaramoorthi, Andrea Mennucci, Stefano So...
TITB
2010
123views Education» more  TITB 2010»
15 years 1 months ago
The pseudotemporal bootstrap for predicting glaucoma from cross-sectional visual field data
Progressive loss of the field of vision is characteristic of a number of eye diseases such as glaucoma, a leading cause of irreversible blindness in the world. Recently, there has ...
Allan Tucker, David Garway-Heath