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CSB
2005
IEEE
168views Bioinformatics» more  CSB 2005»
16 years 1 days ago
cis-Regulatory Element Prediction in Mammalian Genomes
The identification of cis-regulatory elements and modules is an important step in understanding the regulation of genes. We have developed a pipeline capable of running multiple m...
Asim S. Siddiqui, Gordon Robertson, Misha Bilenky,...
CSB
2003
IEEE
121views Bioinformatics» more  CSB 2003»
15 years 11 months ago
Epitope Prediction Algorithms for Peptide based Vaccine Design
Peptide-based vaccines, in which small peptides derived from target proteins (epitopes) are used to provoke an immune reaction, have attracted considerable attention recently as a...
Liliana Florea, Bjarni V. Halldórsson, Oliv...
ISMB
1996
15 years 7 months ago
A Knowledge-Based Method for Protein Structure Refinement and Prediction
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
Shankar Subramaniam, David K. Tcheng, James M. Fen...
ATAL
2010
Springer
15 years 7 months ago
Closing the learning-planning loop with predictive state representations
A central problem in artificial intelligence is to choose actions to maximize reward in a partially observable, uncertain environment. To do so, we must learn an accurate model of ...
Byron Boots, Sajid M. Siddiqi, Geoffrey J. Gordon
BMCBI
2007
133views more  BMCBI 2007»
15 years 6 months ago
AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides
Background: Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's disease...
Oscar Conchillo-Solé, Natalia S. de Groot, ...