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BMCBI
2010
162views more  BMCBI 2010»
15 years 6 months ago
Moara: a Java library for extracting and normalizing gene and protein mentions
Background: Gene/protein recognition and normalization are important preliminary steps for many biological text mining tasks, such as information retrieval, protein-protein intera...
Mariana L. Neves, José María Carazo,...
BMCBI
2010
163views more  BMCBI 2010»
15 years 6 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
BMCBI
2010
178views more  BMCBI 2010»
15 years 6 months ago
CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics
Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
Xiaowu Gai, Juan C. Perin, Kevin Murphy, Ryan O'Ha...
BMCBI
2010
100views more  BMCBI 2010»
15 years 6 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2008
158views more  BMCBI 2008»
15 years 6 months ago
Analyzing M-CSF dependent monocyte/macrophage differentiation: Expression modes and meta-modes derived from an independent compo
Background: The analysis of high-throughput gene expression data sets derived from microarray experiments still is a field of extensive investigation. Although new approaches and ...
Dominik Lutter, Peter Ugocsai, Margot Grandl, Evel...