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BMCBI
2010
117views more  BMCBI 2010»
15 years 6 months ago
Identification of NAD interacting residues in proteins
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
Hifzur Rahman Ansari, Gajendra P. S. Raghava
BMCBI
2010
96views more  BMCBI 2010»
15 years 6 months ago
sdef: an R package to synthesize lists of significant features in related experiments
Background: In microarray studies researchers are often interested in the comparison of relevant quantities between two or more similar experiments, involving different treatments...
Marta Blangiardo, Alberto Cassese, Sylvia Richards...
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2010
149views more  BMCBI 2010»
15 years 6 months ago
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Sigrid Rouam, Thierry Moreau, Philippe Broët
BMCBI
2010
113views more  BMCBI 2010»
15 years 6 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
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