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BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
Predicting population coverage of T-cell epitope-based diagnostics and vaccines
Background: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a...
Huynh-Hoa Bui, John Sidney, Kenny Dinh, Scott Sout...
BMCBI
2006
89views more  BMCBI 2006»
15 years 6 months ago
A joint model for nonparametric functional mapping of longitudinal trajectory and time-to-event
Background: The characterization of the relationship between a longitudinal response process and a time-to-event has been a pressing challenge in biostatistical research. This has...
Min Lin, Rongling Wu
BMCBI
2006
85views more  BMCBI 2006»
15 years 6 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
BMCBI
2006
139views more  BMCBI 2006»
15 years 6 months ago
DNA Molecule Classification Using Feature Primitives
Background: We present a novel strategy for classification of DNA molecules using measurements from an alpha-Hemolysin channel detector. The proposed approach provides excellent c...
Raja Tanveer Iqbal, Matthew Landry, Stephen Winter...
BMCBI
2006
157views more  BMCBI 2006»
15 years 6 months ago
Determination of the minimum number of microarray experiments for discovery of gene expression patterns
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Fang-Xiang Wu, W. J. Zhang, Anthony J. Kusalik
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