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RECOMB
2006
Springer
16 years 7 months ago
Detecting MicroRNA Targets by Linking Sequence, MicroRNA and Gene Expression Data
MicroRNAs (miRNAs) have recently been discovered as an important class of non-coding RNA genes that play a major role in regulating gene expression, providing a means to control th...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2004
151views more  BMCBI 2004»
15 years 6 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
175
Voted
ECMDAFA
2006
Springer
137views Hardware» more  ECMDAFA 2006»
15 years 10 months ago
Harvesting Software Systems for MDA-Based Reengineering
Abstract. In this paper we report on a feasibility study in reengineering legacy systems towards a model-driven architecture (MDA). Steps in our approach consist of (1) parsing the...
Thijs Reus, Hans Geers, Arie van Deursen
GECCO
2003
Springer
16 years 1 days ago
Identifying Structural Mechanisms in Standard Genetic Programming
This paper presents a hypothesis about an undiscovered class of mechanisms that exist in standard GP. Rather than being intentionally designed, these mechanisms would be an uninten...
Jason M. Daida, Adam M. Hilss
HCW
1998
IEEE
15 years 11 months ago
Steps Toward Understanding Performance in Java
Java's design goals of portability, safety, and ubiquity make it a potentially ideal language for large-scale heterogeneous computing. One of the remaining challenges is to c...
Doug Lea