3378 search results - page 168 / 676 » A universe of binding and computation |
161
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BMCBI
2008
15 years 6 months ago
2008
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
184
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BMCBI
2006
15 years 6 months ago
2006
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
169
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BMCBI
2007
15 years 6 months ago
2007
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
201
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BMCBI
2005
15 years 6 months ago
2005
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
168
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BMCBI
2005
15 years 6 months ago
2005
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...