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BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Efficient genome-scale phylogenetic analysis under the duplication-loss and deep coalescence cost models
Background: Genomic data provide a wealth of new information for phylogenetic analysis. Yet making use of this data requires phylogenetic methods that can efficiently analyze extr...
Mukul S. Bansal, J. Gordon Burleigh, Oliver Eulens...
SIGMOD
2008
ACM
107views Database» more  SIGMOD 2008»
16 years 6 months ago
Outlier-robust clustering using independent components
How can we efficiently find a clustering, i.e. a concise description of the cluster structure, of a given data set which contains an unknown number of clusters of different shape ...
Christian Böhm, Christos Faloutsos, Claudia P...
AMAST
2004
Springer
15 years 11 months ago
A Science of Software Design
concerns, abstraction (particularly hierarchical abstraction), simplicity, and restricted visibility (locality of information). The overall goal behind these principles was stated ...
Don S. Batory
BMCBI
2007
174views more  BMCBI 2007»
15 years 6 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BMCBI
2005
100views more  BMCBI 2005»
15 years 5 months ago
Scoredist: A simple and robust protein sequence distance estimator
Background: Distance-based methods are popular for reconstructing evolutionary trees thanks to their speed and generality. A number of methods exist for estimating distances from ...
Erik L. L. Sonnhammer, Volker Hollich