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151
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BMCBI
2007
15 years 6 months ago
2007
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
182
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BMCBI
2008
15 years 6 months ago
2008
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
133
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BMCBI
2007
15 years 6 months ago
2007
Background: Over the past decade, a number of tools have emerged for the examination of homology relationships among protein sequences in a structural context. Most recent softwar...
153
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BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
15 years 6 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
193
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BMCBI
2010
15 years 6 months ago
2010
Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases...