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160
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BMCBI
2010
15 years 6 months ago
2010
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
159
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BMCBI
2010
15 years 6 months ago
2010
Background: Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models...
225
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BMCBI
2010
15 years 6 months ago
2010
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
161
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BMCBI
2010
15 years 6 months ago
2010
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
170
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BMCBI
2010
15 years 6 months ago
2010
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...