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BMCBI
2010
160views more  BMCBI 2010»
15 years 6 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2010
155views more  BMCBI 2010»
15 years 6 months ago
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
BMCBI
2010
153views more  BMCBI 2010»
15 years 6 months ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
permGPU: Using graphics processing units in RNA microarray association studies
Background: Many analyses of microarray association studies involve permutation, bootstrap resampling and crossvalidation, that are ideally formulated as embarrassingly parallel c...
Ivo D. Shterev, Sin-Ho Jung, Stephen L. George, Ko...
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