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BMCBI
2008
152views more  BMCBI 2008»
15 years 6 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
BMCBI
2008
153views more  BMCBI 2008»
15 years 6 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
BMCBI
2008
146views more  BMCBI 2008»
15 years 6 months ago
A phase synchronization clustering algorithm for identifying interesting groups of genes from cell cycle expression data
Background: The previous studies of genome-wide expression patterns show that a certain percentage of genes are cell cycle regulated. The expression data has been analyzed in a nu...
Chang Sik Kim, Cheol Soo Bae, Hong Joon Tcha
BMCBI
2010
83views more  BMCBI 2010»
15 years 6 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf
BMCBI
2007
129views more  BMCBI 2007»
15 years 6 months ago
Integrated network reconstruction, visualization and analysis using YANAsquare
Background: Modeling of metabolic networks includes tasks such as network assembly, network overview, calculation of metabolic fluxes and testing the robustness of the network. Re...
Roland Schwarz, Chunguang Liang, Christoph Kaleta,...
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