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BMCBI
2011
14 years 10 months ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...
CORR
2011
Springer
205views Education» more  CORR 2011»
14 years 10 months ago
Algorithms for Implicit Hitting Set Problems
A hitting set for a collection of sets is a set that has a nonempty intersection with each set in the collection; the hitting set problem is to find a hitting set of minimum card...
Karthekeyan Chandrasekaran, Richard Karp, Erick Mo...
ISPD
2011
ACM
253views Hardware» more  ISPD 2011»
14 years 9 months ago
Assembling 2D blocks into 3D chips
Three-dimensional ICs promise to significantly extend the scale of system integration and facilitate new-generation electronics. However, progress in commercial 3D ICs has been s...
Johann Knechtel, Igor L. Markov, Jens Lienig
JAMIA
2011
140views more  JAMIA 2011»
14 years 9 months ago
Never too old for anonymity: a statistical standard for demographic data sharing via the HIPAA Privacy Rule
Objective Healthcare organizations must de-identify patient records before sharing data. Many organizations rely on the Safe Harbor Standard of the HIPAAPrivacy Rule, which enumer...
Bradley Malin, Kathleen Benitez, Daniel R. Masys
JAMIA
2011
94views more  JAMIA 2011»
14 years 9 months ago
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...